Publications

(2022). BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding. PROTEIN & CELL.

PDF DOI PubMed

(2022). Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos. CELL REPORTS.

PDF DOI PubMed

(2022). 5-methylcytosine modification by Plasmodium NSUN2 stabilizes mRNA and mediates the development of gametocytes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.

PDF DOI PubMed

(2021). The Architectural Factor HMGB1 Is Involved in Genome Organization in the Human Malaria Parasite Plasmodium falciparum.. mBio.

PDF DOI PubMed

(2021). Pyroptosis inhibition improves the symptom of acute myocardial infarction. CELL DEATH & DISEASE.

PDF DOI PubMed

(2021). Optimization of CRISPR/Cas System for Improving Genome Editing Efficiency in Plasmodium falciparum. FRONTIERS IN MICROBIOLOGY.

PDF DOI PubMed

(2021). Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening. ISCIENCE.

PDF DOI PubMed

(2021). Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring. CELL REPORTS.

PDF DOI PubMed

(2021). Dux-Mediated Corrections of Aberrant H3K9ac during 2-Cell Genome Activation Optimize Efficiency of Somatic Cell Nuclear Transfer. CELL STEM CELL.

PDF DOI PubMed

(2021). Differential Transcriptomes and Methylomes of Trophoblast Stem Cells From Naturally-Fertilized and Somatic Cell Nuclear-Transferred Embryos. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY.

PDF DOI PubMed

(2021). Developmental programming and lineage branching of early human telencephalon. EMBO JOURNAL.

PDF DOI PubMed

(2021). Characterizing disease progression of nonalcoholic steatohepatitis in Leptin-deficient rats by integrated transcriptome analysis. EXPERIMENTAL BIOLOGY AND MEDICINE.

PDF DOI PubMed

(2021). An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability. NATURE COMMUNICATIONS.

PDF DOI PubMed

(2021). A cascade of transcriptional repression determines sexual commitment and development in Plasmodium falciparum. NUCLEIC ACIDS RESEARCH.

PDF DOI PubMed

(2020). TCONS_00483150 as a novel diagnostic biomarker of systemic lupus erythematosus. EPIGENOMICS.

PDF DOI PubMed

(2020). Rrp6 Regulates Heterochromatic Gene Silencing via ncRNA RUF6 Decay in Malaria Parasites. MBIO.

PDF DOI PubMed

(2020). Loss of Atg77 causes chaotic nucleosome assembly of mouse bone marrow CD11b(+)Ly6G(-) myeloid cells. AGING-US.

PDF PubMed

(2020). Genome transfer for the prevention of female infertility caused by maternal gene mutation. JOURNAL OF GENETICS AND GENOMICS.

PDF DOI PubMed

(2020). Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos. NATURE COMMUNICATIONS.

PDF DOI PubMed

(2020). A retrospective analysis reveals a predictor of survival for the patient with paraquat intoxication. CLINICA CHIMICA ACTA.

PDF DOI PubMed

(2019). Wingless modulates activator protein-1-mediated tumor invasion. ONCOGENE.

PDF DOI PubMed

(2019). TRIBE Uncovers the Role of Dis3 in Shaping the Dynamic Transcriptome in Malaria Parasites. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY.

PDF DOI PubMed

(2019). Increase in DNA Damage by MYCN Knockdown Through Regulating Nucleosome Organization and Chromatin State in Neuroblastoma. FRONTIERS IN GENETICS.

PDF DOI PubMed

(2019). Improved recombinant protein production by regulation of transcription and protein transport in Chinese hamster ovary cells. BIOTECHNOLOGY LETTERS.

PDF DOI PubMed

(2019). H3K27me3 Signal in the Cis Regulatory Elements Reveals the Differentiation Potential of Progenitors During Drosophila Neuroglial Development. GENOMICS PROTEOMICS & BIOINFORMATICS.

PDF DOI PubMed

(2019). Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks. GENOME RESEARCH.

PDF DOI PubMed

(2019). Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN. THERANOSTICS.

PDF DOI PubMed

(2019). Chemical cocktails enable hepatic reprogramming of human urine-derived cells with a single transcription factor. ACTA PHARMACOLOGICA SINICA.

PDF DOI PubMed

(2019). Alyref is a novel binding partner and co-factor for MYCN-driven oncogenesis in neuroblastoma. CANCER RESEARCH.

PDF DOI PubMed

(2019). A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites. NUCLEIC ACIDS RESEARCH.

PDF DOI PubMed

(2018). Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification. CELL DEATH & DISEASE.

PDF DOI PubMed

(2018). Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency. NUCLEIC ACIDS RESEARCH.

PDF DOI PubMed

(2018). Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b. STEM CELL REPORTS.

PDF DOI PubMed

(2018). Genome-wide DNA methylation analysis reveals that mouse chemical iPSCs have closer epigenetic features to mESCs than OSKM-integrated iPSCs. CELL DEATH & DISEASE.

PDF DOI PubMed

(2018). Dynamic placement of the linker histone H1 associated with nucleosome arrangement and gene transcription in early Drosophila embryonic development. CELL DEATH & DISEASE.

PDF DOI PubMed

(2018). Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers. NUCLEIC ACIDS RESEARCH.

PDF DOI PubMed

(2018). Accurate annotation of accessible chromatin in mouse and human primordial germ cells. CELL RESEARCH.

PDF DOI PubMed

(2017). The temporal requirements for Isl1 in sympathetic neuron proliferation, differentiation and diversification. MECHANISMS OF DEVELOPMENT.

PDF DOI PubMed

(2017). Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis. CELL RESEARCH.

PDF DOI PubMed

(2017). Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment. CELL DEATH AND DIFFERENTIATION.

PDF DOI PubMed

(2017). Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY.

PDF DOI PubMed

(2017). Chromatin remodeling during in vivo neural stem cells differentiating to neurons in early Drosophila embryos. CELL DEATH AND DIFFERENTIATION.

PDF DOI PubMed

(2017). Chromatin remodeling and its epigenetic regulatory mechanisms in cell fate transition. Chinese Bulletin of Life Sciences.

PDF PubMed

(2016). The long noncoding RNA MALAT1 promotes tumor-driven angiogenesis by up-regulating pro-angiogenic gene expression. ONCOTARGET.

PDF DOI PubMed

(2016). The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog. NATURE COMMUNICATIONS.

PDF DOI PubMed

(2016). Targeted Differentiation of Regional Ventral Neuroprogenitors and Related Neuronal Subtypes from Human Pluripotent Stem Cells. STEM CELL REPORTS.

PDF DOI PubMed

(2016). Smad2 and Smad3 have differential sensitivity in relaying TGF beta signaling and inversely regulate early lineage specification. SCIENTIFIC REPORTS.

PDF DOI PubMed

(2016). Profiling Analysis of Histone Modifications and Gene Expression in Lewis Lung Carcinoma Murine Cells Resistant to Anti-VEGF Treatment. PLOS ONE.

PDF DOI PubMed

(2016). Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and beta-catenin. CIRCULATION.

PDF DOI PubMed

(2016). Naive Induced Pluripotent Stem Cells Generated From beta-Thalassemia Fibroblasts Allow Efficient Gene Correction With CRISPR/Cas9 (vol 5, pg 8, 2016). STEM CELLS TRANSLATIONAL MEDICINE.

PDF DOI PubMed

(2016). Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. CELL.

PDF DOI PubMed

(2016). Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation. SCIENCE CHINA-LIFE SCIENCES.

PDF DOI PubMed

(2016). Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming. CELL REPORTS.

PDF DOI PubMed

(2016). Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production. MOLECULAR BIOSYSTEMS.

PDF DOI PubMed

(2016). Distinct response of the hepatic transcriptome to Aflatoxin B-1 induced hepatocellular carcinogenesis and resistance in rats. SCIENTIFIC REPORTS.

PDF DOI PubMed

(2016). dFoxO promotes Wingless signaling in Drosophila. SCIENTIFIC REPORTS.

PDF DOI PubMed

(2016). Chromatin remodeling during the in vivo glial differentiation in early Drosophila embryos. SCIENTIFIC REPORTS.

PDF DOI PubMed

(2015). Transcription factor ISL1 is essential for pacemaker development and function. JOURNAL OF CLINICAL INVESTIGATION.

PDF DOI PubMed

(2015). The microRNA Signatures in Mouse Liver Ischemia Reperfusion Injury. TRANSPLANTATION.

PDF PubMed

(2015). Pwp1 Is Required for the Differentiation Potential of Mouse Embryonic Stem Cells Through Regulating Stat3 Signaling. STEM CELLS.

PDF DOI PubMed

(2015). Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells. SCIENTIFIC REPORTS.

PDF DOI PubMed

(2015). Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails. CELL RESEARCH.

PDF DOI PubMed

(2014). Tumor resistance to anti-VEGF therapy through up-regulation of VEGF-C expression. CANCER LETTERS.

PDF DOI PubMed

(2014). Toxic effects of decabromodiphenyl ether (BDE-209) on human embryonic kidney cells. FRONTIERS IN GENETICS.

PDF DOI PubMed

(2014). Severe hypoxia exerts parallel and cell-specific regulation of gene expression and alternative splicing in human mesenchymal stem cells. BMC GENOMICS.

PDF DOI PubMed

(2014). Phylogenetic affinity of tree shrews to Glires is attributed to fast evolution rate. MOLECULAR PHYLOGENETICS AND EVOLUTION.

PDF DOI PubMed

(2014). Nucleosome organizations in induced pluripotent stem cells reprogrammed from somatic cells belonging to three different germ layers. BMC BIOLOGY.

PDF DOI PubMed

(2014). Gene Expression Profiling Analysis of Bisphenol A-Induced Perturbation in Biological Processes in ER-Negative HEK293 Cells. PLOS ONE.

PDF DOI PubMed

(2014). Epigenetics: the language of the cell?. EPIGENOMICS.

PDF DOI PubMed

(2014). Drosophila Brahma complex remodels nucleosome organizations in multiple aspects. NUCLEIC ACIDS RESEARCH.

PDF DOI PubMed

(2013). VEGF-Mediated Proliferation of Human Adipose Tissue-Derived Stem Cells. PLOS ONE.

PDF DOI PubMed

(2013). TFPP: An SVM-Based Tool for Recognizing Flagellar Proteins in Trypanosoma brucei. PLOS ONE.

PDF DOI PubMed

(2013). Ribosomal RNA Gene Transcription Mediated by the Master Genome Regulator Protein CCCTC-binding Factor (CTCF) Is Negatively Regulated by the Condensin Complex. JOURNAL OF BIOLOGICAL CHEMISTRY.

PDF DOI PubMed

(2013). Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC BIOLOGY.

PDF DOI PubMed

(2013). PEpiD: A Prostate Epigenetic Database in Mammals. PLOS ONE.

PDF DOI PubMed

(2013). microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. CELL RESEARCH.

PDF DOI PubMed

(2013). H2A.Z Nucleosome Positioning Has No Impact on Genetic Variation in Drosophila Genome. PLOS ONE.

PDF DOI PubMed

(2012). Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium. GENOME RESEARCH.

PDF DOI PubMed

(2012). MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway. JOURNAL OF BIOLOGICAL CHEMISTRY.

PDF DOI PubMed

(2011). A Comprehensive Genomic Binding Map of Gene and Chromatin Regulatory Proteins in Saccharomyces. MOLECULAR CELL.

PDF DOI PubMed

(2010). Features of Recent Codon Evolution: A Comparative Polymorphism-Fixation Study. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY.

PDF DOI PubMed

(2009). Nucleosome positioning and gene regulation: advances through genomics. NATURE REVIEWS GENETICS.

PDF DOI PubMed

(2009). Interaction of Transcriptional Regulators with Specific Nucleosomes across the Saccharomyces Genome. MOLECULAR CELL.

PDF DOI PubMed

(2009). Identification and Nomenclature of the Consensus Nucleosomes Across the Yeast Genome. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS.

PDF PubMed

(2008). Nucleosome organization in the Drosophila genome. NATURE.

PDF DOI PubMed

(2008). NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila. MOLECULAR AND CELLULAR BIOLOGY.

PDF DOI PubMed

(2008). GeneTrack - a genomic data processing and visualization framework. BIOINFORMATICS.

PDF DOI PubMed

(2008). Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH.

PDF DOI PubMed

(2008). A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome. GENOME RESEARCH.

PDF DOI PubMed

(2007). Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes. MOLECULAR BIOLOGY AND EVOLUTION.

PDF DOI PubMed

(2004). Ordered origin of the typical two- and three-repeat Myb genes. GENE.

PDF DOI PubMed

(1998). Studies on microdissection and microcloning of the rye chromosome 1R. ACTA BOTANICA SINICA.

PDF PubMed